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Is bigger always better in research? A clinical scientist's perspective on big science vs small science — and why modest budgets often...

Should you post your research as a preprint? A balanced look at the visibility benefits, peer review concerns and reputational risks authors...

How the digital age has transformed the way we communicate, share information, and consume content.

List making reduces cognitive load, triggers dopamine and helps manage anxiety. A look at the psychology behind why lists work and how to...

How meaningful conversations build trust, improve wellbeing, and why authenticity matters more than ever in a digital-first world.

An outdated LinkedIn photo can undermine trust before you say a word. Why keeping your profile picture current matters for professional...

In the past, Halloween has meant the end of the crop and the start of the dark, cold winter.

Frights create a happy Halloween by providing the thrill of fear in a controlled and safe environment, turning what would normally be...

Halloween is upon us again.

Half of clinical guidelines are outdated within 6 years. How should medicine respond to the shrinking shelf life of medical knowledge in an...

With the year coming to a close, the Niche team are eager to thank all our colleagues

Most writers fear judgement of their work. Practical techniques for reviewing your own writing objectively and building confidence as a...

AI can make your writing perfect but at what cost? A look at cognitive debt, authenticity and why the human fingerprint still matters more...

ChatGPT is reshaping medical writing and scientific communication. A critical look at the benefits, limitations and risks of AI in research...

Innovation in health communications is not about new tools. A look at AI risks, intent driven strategies and what meaningful progress...

A pun that travels the galaxy. How Star Wars Day uses humour, awe and cultural storytelling to make science accessible and why that matters...

It can feel like a career in science is about sacrifice.

Unfortunately, health does not generally improve with age.

Promotion in medical writing is rarely about time served. A candid look at what actually drives career progression and why growth matters...

Can anyone become an instant expert? Cognitive science explains the limits of rapid learning, shallow knowledge, and the illusion of...

From gene therapy to cancer immunotherapy, 2012 marked a quiet inflection point in medicine. A look back at the advances that shaped modern...

We have some strange terms in the pharma industry

With the year coming to a close, the Niche team are eager to thank all our colleagues

Chronic overwhelm is the real workplace horror. A look at the cognitive science of workplace fear, multitasking overload and why delegation...

Predatory journals feed off scientific research. A Halloween look at the monsters lurking inside academic publishing and who the real...

Senescent cells refuse to die and poison the tissues around them. Discover the science of cellular senescence, inflammaging and the drugs...

I am shamelessly referencing our Insider’s Insights (IIs) to Dr Who’s TARDIS – our latest edition

How common are uncited research papers? A closer look at publication metrics, bibliometrics, and what citation counts really say about...

Want a conversation to warm your heart and lift your spirits

Research shows handwriting notes may improve focus and memory compared with typing. Discover why the pen may still outperform the laptop.

By their very nature, experts don't find humour funny. We take things way too literally.

Shy, introverted, or just dreading the coffee queue? Practical strategies for scientists and clinicians to network confidently at...

A lot of people say that people don't just buy 'things,' they buy connection

Learn how lean medical writing improves clarity, reduces regulatory document length, and helps reviewers understand clinical data faster.

Even though I'm not particularly religious

At a time when the news seems to enjoy focusing on bad things

The largest pharmaceutical companies not surprisingly rely on the largest contract research organizations

They say that as one door closes another one opens.

How remote work, AI tools and pandemic disruption are reshaping burnout in the pharmaceutical industry and what leaders must do to respond.

Does handwriting improve learning compared with typing or AI transcription? Explore the science behind note taking and memory.

At the start of the year many of us faced changes to the way we work as the COVID-19

Journal selection has become a strategic scholarly activity rather than a final administrative step in the research process.

How daylight saving time affects sleep, heart health, mood, and safety. Evidence from circadian science explains why many experts support...

New EUFEMED data explains why healthy volunteers join Phase I trials and how better participant experience improves research.

Metathesiophobia: from Preclinical to Clinical Development

With the year coming to a close, the Niche team

Since 2013, our Insider's Insights have been a way for Niche

In the words of Clint Eastwood’s character, Harry Callahan, in the film Magnum Force “A man's got to know his limitations”....

Last week was the 20-year anniversary of my founding Niche Science & Technology Ltd.

It the time of school retrospectives once again

We have long been confounded by that indescribable phenomenon known as love.

Early in 2020, COVID-19 was spreading rapidly across the globe.

We recently encouraged writers (of all kinds) in our recent Insider’s Insight to experiment with large language artificial intelligence...

Every year, a huge amount of scientific data is released. It's out there, but how do you find it?

Music has a remarkable ability to bring people together and permeate

Whether it’s a festival, concert or celebratory party, music unites people and pervades

Paraskevidekatriaphobia is a phobia of Friday the 13th. Yes, they actually gave it a name.

Biologic therapies for severe asthma, monoclonal antibodies targeting key type‑2 inflammatory pathways.

As a jobbing scientist you rarely spend your whole career working on the same project.

We have some strange terms in the pharma industry

Buying Christmas presents for people can be difficult

I believed that the central purpose of journalism is to provide the general population

I was planning to post an article on mentorship today

Posters are an excellent opportunity to showcase your work

The festive season is upon us again.

I've been studying medicine for 40 years, and it's beginning to look like something out of science fiction

When a country’s economy becomes so dominated by a single export industry

In 1786, estimates placed our average life expectancy at just 24 years.

With the year coming to a close, the Niche team are eager to thank all our colleagues

The scientific literature comprises scholarly publications that report original

Yes, it’s Star Wars Day again! The Star Wars films base their wow-factor on their adoption of science

Son, I wanted to record this landmark day in your progress through life.

I am continually reminded that I must work toward better relationships with my sons than the one I had with my dad.

The UK's world-class human challenge study gives us new information about SARS-CoV-2 cases that were mild in 36 healthy young volunteers who...

I love this time of year because I love fireworks. Did a love of fireworks spark a lifelong interest in science? When I was about 11, a...

Work never stops and after the findings of our ground breaking survey in the EMWA

The US Army has a new secret weapon – napping.

When the UK went into lockdown on March 23rd because of the COVID-19 outbreak,

May 4 is often known as ‘Star Wars Day’. It is jokingly said

Over the years friends, colleagues and industry leaders have shared their many of their insights with me freely

Attend any research meeting, conference or clinical congress

We all have a responsibility to encourage young people to study science

We should all do what we can to get young people interested

Last night saw a collection of the UK’s great and the good in clinical pharmacology

We use the term coming of age to describe the transition into adulthood

The festive season is a time for the giving and receiving of gifts.

Last week marked 12 months since I was involved in a life-changing accident.

In response to my post with tips for people who want to start their own business

On this day 2 years ago I had a pretty bad accident getting knocked off my motorbike

The last 20 years at Niche have been amazingly exciting – offering

Yesterday was 20 years since the Memorandum

on the occasion of your becoming an adult.

It is possible to use electrodes to record brain

My end-of-year task for yesterday was a visit the local police station

Academic Industry Meeting days (AIMdays)

This is me, close to death – again.

Many of the increasing number of elderly in our population

We are looking over the precipice that is a revolution

We are looking over the precipice that is a revolution in lifespan modification.

According to many observers we are standing on the precipice