Research

The question is whether clinical research is approaching its greatest methodological upheaval since the development of the randomised,...

Over the past two decades, drug discovery has been transformed across multiple therapeutic areas. Yet this remarkable progress has largely...

The persistent challenge in drug development has long been its high attrition rate, with late-stage failures frequently tracing back to...

What is all the excitement around digital twins?

Writing is not a constant skill but a fluctuating state. A look at how circadian rhythms, music and environment shape creativity and how...

Why pharmaceutical research wastes most of the data it generates and how AI and LLMs are beginning to unlock its hidden scientific value.

Semantic search tools can find relevant papers without exact keyword matches.

Some scientific discoveries emerge from careful planning. Others arrive by accident as with this clinical study into long COVID.

The FDA is monitoring live clinical trial data using AI in a landmark pilot with AstraZeneca and Amgen. What real-time oversight could mean...

Half of clinical guidelines are outdated within 6 years. How should medicine respond to the shrinking shelf life of medical knowledge in an...

Omnichannel is giving way to intent driven communication. What does this mean for scientific dissemination and how findings reach decision...

From ghost authorship to AI, scientific authorship has changed beyond recognition. A 40 year perspective on credit, contribution and...

AI is reshaping how scientists create figures. We explore the opportunities, ethical risks and practical guidelines for responsible use in...

Gene therapy has transformed care for rare diseases — but is it a scalable future for medicine? A critical look at the costs, complexity...

Could mass weight loss from GLP-1 drugs generate a measurable CO₂ pulse? We explore the carbon science behind obesity pharmacotherapy —...

How remote work, AI tools and pandemic disruption are reshaping burnout in the pharmaceutical industry and what leaders must do to respond.

Does handwriting improve learning compared with typing or AI transcription? Explore the science behind note taking and memory.

New EUFEMED data explains why healthy volunteers join Phase I trials and how better participant experience improves research.

How daylight saving time affects sleep, heart health, mood, and safety. Evidence from circadian science explains why many experts support...

A practical guide to building a minimum viable QMS for biotech companies preparing first-in-human trials, covering essential SOPs,...

Why biotech and medical device start ups gain agility, integrated expertise, and strategic advantage by partnering with small CRO teams.

The EMA has approved Waskyra for Wiskott Aldrich Syndrome. A personal reflection on Niche's decade long role in this gene therapy's...

Learn how lean medical writing improves clarity, reduces regulatory document length, and helps reviewers understand clinical data faster.

In a landmark shift, the US Food and Drug Administration (FDA) has announced plans to reduce its reliance on traditional animal testing...

Is the perception of declining standards just curmudgeon bias, or is something genuinely eroding in science and pharma? A look at the...

We use questions to organise knowledge, identify gaps in understanding and drive decision-making. The effectiveness of a question determines...

Brainstorming has long been regarded as an essential component of creative problem-solving, particularly in collaborative environments.

The Second MID-Frail Publication: Demonstrating That Frailty in Older Adults with Diabetes Can Be Reversed

A fascinating science news story hit the headlines in the last 24 hours, that a common over-the-counter ingredient in many cough syrups may...

Clinical trial complexity has risen over 10% in a decade, driving longer timelines and higher failure rates. A look at what sponsors can do...

Investigator sites are very important to clinical studies because they make sure that new drugs are safe and work well.

Every year, a huge amount of scientific data is released. It's out there, but how do you find it?

The UK's world-class human challenge study gives us new information about SARS-CoV-2 cases that were mild in 36 healthy young volunteers who...

There have been hundreds of thousands of deaths from COVID-19

The sudden imposition of remote working in response to the 2020 COVID-19

Phenotype-specific omic expression patterns in people with frailty could provid

The comparison of the DPP4 (dipeptidyl peptidase 4) SARS-CoV-2

When the UK went into lockdown on March 23rd because of the COVID-19 outbreak,

Grant writing is an art, but it is also a discipline. Treat it with the same care you apply to your experiments, and you may find yourself...

Attend any research meeting, conference or clinical congress

Last night saw a collection of the UK’s great and the good in clinical pharmacology

Our publication on effectiveness of a multimodal intervention

ive years ago I was lucky enough to be involved in a project that resulted in publications

Because new biologic treatments for asthma can be expensive and cause side effects,

Research into the remarkable regenerative powers of the flatworm Macrostomum lignano a

It was encouraging to see so many partners at the 2017 General Assembly meeting last December

How common are uncited research papers? A closer look at publication metrics, bibliometrics, and what citation counts really say about...

From Index Medicus to PubMed in seconds. A personal reflection on how scientific literature searching has changed and what the old ways...

Publication planning provides the framework through which research findings are transformed into scientific knowledge and societal benefit.

RASP-UK underwent its third progress review by the MRC on 19 May.

You may think that 'writing the abstract' simply  involves summarising

Welcome to the latest edition of the Frailomic Initiative Newsletter.

Welcome to the Frailomic Newsletter Update for 2016.

1,963 search results and a 6 week deadline. A practical triage system for finding and extracting value from scientific literature for your...

Explore how women’s exclusion from clinical trials shaped medicine and why sex-specific data is essential for precision healthcare today.

Deep Breath is the official newsletter of the UKs Refactory Asthma

Read the latest newsletter from both our MID-Frail

Our publication on the potential benefits of bariatric surgery

Our publication on sarcoidosis, a multisystem inflammatory disease

Frailty has a dramatic impact on the quality of life of many elderly people

ur publication on new therapies to reduce low-density

Medical writing demands more than good grammar. A seasoned perspective on the technical skills, soft skills and resilience needed to thrive...

Today we had our manuscript on the pre-protein convertase subtilisin kexin (PCSK)-9

MID‐Frail News returns with this Special Issue to report on the project development

Welcome to the first issue of the MID‐Frail newsletter

Epidemiological data suggest that at two in five of us will experience

Qualitative and quantitative research serve different purposes. An overview of their philosophical foundations, methods, strengths and when...