
Deep Breath is the official newsletter of the UKs Refactory Asthma Stratification Programme and you can read our first issue here [1].
Our consortium of research, academic and industry parties are focused on finding new treatment paradigms for asthma. We see the future of severe asthma management involving treatment optimisation to individual patients fully utilising currently available treatments more efficiently, particularly with corticosteroids by defining an ‘optimised’ dose, allied with the use of ‘add-on’ target-specific novel treatments. At present there seems to a “tsunami” of novel treatments aimed at targeting Type-2 cytokine mediated inflammation approaching introduction in the clinic. Understanding where these new treatments will fit into the current management is likely to define our therapeutic journey in the coming years. This new ‘era’ and our collaborative efforts in this UK clinical research programme will hopefully deliver better management for our patients as well as contribute to the identification of novel targets in this exciting era of stratified medicines in severe asthma.
This newsletter gives a description of the various different work strands on the initiative and their objectives, introduces key team members and provides an update on the progress being made by each of the different aspects of the project. There is a brief report on the first RASP-UK General Assembly Meetng held on 1st December 2015 at One Drummond Gate, Victoria, London. This was the first time all consortium leaders and key members of their teams had gathered in one place and it was a great opportunity for the consortium to share their experience, cement relationships that will foster collaboration and receive updates from the leadership team relating to the RASP-UK programme. One of the key objectives of the bringing the teams together was to introduce the multidisciplinary teams to the concept of achieving project legacy through a strategically targeted process of publication planning and communications designed to win share of voice in the rapidly developing field of asthma treatment. Further information can be found on the consortium website [2].


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I am shamelessly referencing our Insider’s Insights (IIs) to Dr Who’s TARDIS – our latest edition
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7th January 2015
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ive years ago I was lucky enough to be involved in a project that resulted in publications
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Have you seen our latest Insider's Insight on Case Reports? Once a staple of medical journals,
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4th July 2020
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19th October 2018
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10th July 2018
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6th December 2019
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21st December 2020
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27th January 2023
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The clinical stage biotechnology company developing breakthrough therapies for patients suffering with cancer,
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20th December 2020
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26th June 2019
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25th February 2021
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11th May 2023
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Investigator sites are very important to clinical studies because they make sure that new drugs are safe and work well.
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3rd May 2016
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9th January 2014
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4th April 2023
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8th September 2020
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20th April 2023
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Every year, a huge amount of scientific data is released. It's out there, but how do you find it?
12th July 2013
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22nd January 2019
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29th October 2021
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Frights create a happy Halloween by providing the thrill of fear in a controlled and safe environment, turning what.
27th July 2023
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Investigator-Initiated Clinical Trials (IITs) are clinical studies led by academic researchers or clinicians
3rd February 2022
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The UK's world-class human challenge study gives us new information about SARS-CoV-2 cases that were mild in 36 healthy.
8th July 2016
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9th May 2015
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14th February 2022
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23rd July 2015
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24th March 2025
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12th May 2012
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21st April 2012
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17th February 2022
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When I was younger, the opening lines of the Beatle’s seminal ‘Sgt. Pepper’s Lonely Hearts Club Band’ resonated.
16th August 2020
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2nd November 2023
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3rd July 2019
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15th May 2017
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1st September 2014
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19th November 2018
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The proceedings of the Association for Human Pharmacology in the Pharmaceutical Industry (AHPPI)
3rd March 2015
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16th April 2017
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9th February 2016
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4th January 2019
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18th March 2021
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12th July 2017
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31st March 2021
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2nd September 2016
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14th August 2018
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The largest pharmaceutical companies not surprisingly rely on the largest contract research organizations
6th July 2018
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It was encouraging to see so many partners at the 2017 General Assembly meeting last December
2nd July 2020
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28th March 2025
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4th February 2014
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27th January 2023
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Concerns about readiness of the European Medicines Agency’s (EMA) Clinical Trials Information System persist as the.
2nd March 2021
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12th March 2012
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31st May 2023
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Advisory board meetings are often used to address perceived knowledge gaps and build consensus.
8th September 2013
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4th May 2020
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5th August 2019
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Welcome to the seventh issue of the Refractory Asthma Stratification Programme (RASP-UK) newsletter
25th October 2019
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17th April 2012
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1st September 2015
- Tim Hardman
19th June 2018
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Experience at Niche has taught us that clinical study protocols are born in the white-hot fire
22nd July 2021
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Rational Vaccines (RVx) announces MHRA Innovation Licensing and Access Pathway (ILAP) approval for their live attenuated.
6th October 2016
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1st July 2014
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12th September 2013
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17th July 2017
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3rd December 2012
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