
Our publication on the potential benefits of bariatric surgery in obese older people, work that followed on from our MID-Frail and Frailomic studies, was published in the journal Cardiovascular Endocrinology today [1]. The aim of the Niche team was to determine whether older (≥65 years) obese people would benefit from bariatric surgery, considering prevalence of multiple comorbidities and frailty in this group.
This was literature-based investigation where a PubMed search was carried out seeking studies on the use of bariatric surgery in the target population between the dates 1980 to present (August 2014). Two hundred and forty-four citations were obtained; 182 of these publications were selected for manual checking and 10 studies were identified as containing useable data on this patient cohort. Published data were available for efficacy in 641 patients. The data indicated substantial improvements in diabetes (76%), hypertension (68%) and sleep apnoea (67%) following bariatric surgery. Laparoscopic adjustable gastric banding (n=456) was the most frequently reported procedure. Similar findings but with greater weight loss and fewer complications were found in the small numbers of patients undergoing other procedures. Data from four large registry studies (n=6837) showed mortality and complications associated with bariatric surgery to be increased in older people compared with younger especially in those undergoing gastric bypass surgery. The elderly had longer hospital stays, and patients with cardiac, pulmonary or renal comorbidities generally had a worse prognosis.
The study concludes that bariatric surgery in older people is not only effective in reducing complications of obesity but is also associated with increased rates of complications compared with those seen in younger patients. The few reported studies in the elderly are retrospective, generally small, primarily describe findings of laparoscopic adjustable gastric banding as the surgical intervention option and lack long-term follow-up. More trials and registry data, especially for sleeve gastrectomy and gastric bypass, are required to better address the utility of bariatric surgery in the elderly and to define long-term clinical outcomes.
References


25th October 2019
- Tim Hardman
5th August 2019
- Tim Hardman
Welcome to the seventh issue of the Refractory Asthma Stratification Programme (RASP-UK) newsletter
26th June 2019
- Tim Hardman
6th April 2016
- Tim Hardman
21st April 2012
- Tim Hardman
25th April 2019
- Tim Hardman
31st March 2021
- Tim Hardman
9th February 2016
- Tim Hardman
21st December 2020
- Tim Hardman
6th July 2018
- Tim Hardman
It was encouraging to see so many partners at the 2017 General Assembly meeting last December
18th March 2021
- Tim Hardman
15th February 2018
- Tim Hardman
31st January 2017
- Tim Hardman
1st July 2014
- Tim Hardman
4th August 2021
- Tim Hardman
Since 2013 we have been sharing our understanding on key issues with friends and clients via our Insider’s Insights.
1st July 2013
- Tim Hardman
2nd June 2015
- Tim Hardman
6th September 2017
- Tim Hardman
29th March 2021
- Tim Hardman
23rd April 2019
- Tim Hardman
2nd November 2023
- Tim Hardman
13th December 2018
- Tim Hardman
12th May 2020
- Tim Hardman
3rd February 2022
- Tim Hardman
The UK's world-class human challenge study gives us new information about SARS-CoV-2 cases that were mild in 36 healthy.
24th February 2020
- Tim Hardman
Finding the best vehicle in which to publish your research findings is a perennial challenge.
1st September 2014
- Tim Hardman
10th July 2018
- Tim Hardman
14th February 2022
- Tim Hardman
2nd March 2021
- Tim Hardman
19th October 2018
- Tim Hardman
11th May 2023
- Tim Hardman
Investigator sites are very important to clinical studies because they make sure that new drugs are safe and work well.
1st April 2017
- Tim Hardman
2nd July 2020
- Tim Hardman
12th July 2013
- Tim Hardman
28th February 2019
- Tim Hardman
ive years ago I was lucky enough to be involved in a project that resulted in publications
9th February 2021
- Tim Hardman
9th May 2017
- Tim Hardman
20th April 2023
- Tim Hardman
Every year, a huge amount of scientific data is released. It's out there, but how do you find it?
26th February 2019
- Tim Hardman
8th September 2020
- Tim Hardman
29th March 2019
- Tim Hardman
7th June 2022
- Tim Hardman
17th April 2012
- Tim Hardman
6th December 2019
- Tim Hardman
2nd September 2016
- Tim Hardman
12th May 2012
- Tim Hardman
4th July 2020
- Tim Hardman
12th March 2012
- Tim Hardman
19th November 2018
- Tim Hardman
The proceedings of the Association for Human Pharmacology in the Pharmaceutical Industry (AHPPI)
27th July 2023
- Tim Hardman
Investigator-Initiated Clinical Trials (IITs) are clinical studies led by academic researchers or clinicians
1st April 2019
- Tim Hardman
22nd January 2019
- Tim Hardman
Get our latest news and publications
Sign up to our news letterResources
Contact us
Address
Niche Science & Technology
Unit 26 Falstaff House
Bardolph Road
Richmond TW9 2LH
United Kingdom
Regular Updates

