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Frailomic newsletter #4

January 9, 2015
 - Tim Hardman

In the UK we have a saying that you wait hours for a bus and then two come along at once. Well, it seems that in this case FRAILOMIC newsletters are like buses! We have another update on the Frailomic consortium following on quickly from our previous on in December. You can download the latest issue [1].

In the current issue we report on the annual 2-day Frailomic gathering that was held in Mallorca last November. The meeting served as an opportunity for the consortium partners to update each other on the project’s achievements and advances. The exploratory phase of the study was designed to ensure that all biological samples from each cohort were delivered successfully to the laboratories involved. These samples have been received and processed over the course of the last year, and this phase should be completed by the end of this month. The second phase of Frailomic, the validation phase, will include cohorts from ENRICA, SARDINIA, MAPT, SAGE and COURAGE (WHO cohorts), and ETES. A meeting will be arranged in January 2015 to consider key information regarding each cohort (for example, types of clinical and biological information available, types and amounts of samples available, and any legal or ethical issues that are specific to any cohort). Full information is provided on the study website [2].

Day 1 was mostly taken up with partner organisations reporting on progress they have made on analysing the samples. Emphasis on Day 2 was placed on discussion of the various study cohorts and the approach to the statistical analysis. The Niche team reported on how the first manuscript in the Frailomic publication plan had been submitted to the journal Gerontology and it was decided during the meeting that the second and third manuscripts would be combined into a single submission.

References

  1. Frailomic consortium newsletter #4
  2. www.frailomic.org

About the author

Tim Hardman
Managing Director
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Dr Tim Hardman is Managing Director of Niche Science & Technology Ltd., a bespoke services CRO based in the UK. He also serves as Managing Director at Thromboserin Ltd., an early-stage biotechnology company. Dr Hardman is a keen scientist and an occasional commentator on all aspects of medicine, business and the process of drug development.

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